• Dr Cog
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    1 year ago

    Yes, but Adderall is dextroamphetamine, the drug Vyvanse turns into.

    I’m familiar with the pharmacology and their respective mechanisms, just stating that they’re essentially the same drug

    • TheTimeKnife@lemmy.world
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      1 year ago

      They are not the same drug, reread what I said. You can’t be very familiar with pharmacology if you don’t understand prodrugs. They turn into almost Adderall, which isn’t straight dextroamphetamine. This changes how they effect the body, you can say “essentially the same” all you want, but it’s not true when it comes to how they actually impact people. Differing metabolic rates due to naturally different levels of metabolizing enzymes causes prodrugs to have more variance in their peak blood serum levels, it causes later onset of effect and can cause large variance in duration of effect. This can be very helpful or even dangerous for some people. They are not perfectly interchangeable, even if most people find them pretty similar.

      • grysbok@lemmy.sdf.org
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        1 year ago

        Thank you. Adderall (amphetamine + dextroamphetamine) gave me intolerable side-effects at the minimum effective dose for me. That’s my doctor moved me to dextroamphetamine, which has been lovely. They are not the same.

      • Dozzi92@lemmy.world
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        1 year ago

        Unrelated comment: I’m interested in following this exchange, but it’s collapsed, dunno if the pic embeds here or what. I click, jerboa crashes, rinse and repeat. I dunno, just felt like talking about. Dunno if anyone else has had similar dysfunction.