Wikipedia pages for each:
https://en.m.wikipedia.org/wiki/Prey_(2017_video_game)
https://en.m.wikipedia.org/wiki/Prey_(2006_video_game)
It’s a bit of an apples and oranges situation but considering the history I’m curious which one people prefer in a situation where you could only have one. I believe 2006 is still considered abandonware with it previously being listed on Steam but being removed when they ran out of keys.
I liked 2017’s gameplay but I felt like 2006 was more memorable and unique so I think I’d choose it.
They are completely unrelated. They just had a really cool name they didn’t want to lose.