My dream Mythbusters would be Allen Pan and Grady Hillhouse as the hosts, with Jabrils, Michael Reeves, and Simone Giertz as the build team. I feel like that covers all the bases. The funny guy and straight man hosts, and the computer guy, adrenaline addict, and levelheaded smart woman build team, with frequent guest hosts William Osman, Kevin Backyardscientist, Nigel Braun, Alex Apollonov, and James Hobson

There are so many people with such dense resumes and existing fanbases, and Discovery hired two, uh, guys. No offense to Jon and Brian, I just like everyone else named in this comment better