Given the events of “Picard” and the delays of the writer’s strike, it’s considerably less likely we’ll get to see our old Q up to no good. Natasha has the smarmy attitude expected from a Q, so why not? Certainly welcome to a relative unknown in the role if they can pull it off, but she gets my vote.
I propose Diane Morgan, in character as Philomena Cunk. Just cause they’re immortal doesn’t mean every Q needs to be a semi-malicious super genius. Trek needs an omnipresent goober