As with Colossal’s mammoth plans, TIGRR intends to obtain thylacine genomes, identify key differences between that genome and related lineages (mostly quolls), and then edit those differences into marsupial stem cells, which would then be used for IVF. It, too, faces some significant hurdles, in that nobody has made marsupial stem cells yet, nor has anyone cloned a marsupial—two things that have at least been done in placental mammals (though not pachyderms).