Open Research Europe (ORE) is the peer-reviewed open-access publishing platform of the European Commission. It follows the post-publication peer review model to promote scientific transparency and reuse. The Commission plans to develop an infrastructure to underpin ORE in the future that is based on open source software following the open-source code use and distribution model. The present analysis was commissioned to determine if open-source software (OSS) solutions can be used as a foundation for developing the new publishing platform and to document the necessary workflows and functionalities of the new platform. After conducting a thorough analysis, it has become evident that utilizing existing open-source software has its own advantages and disadvantages. Although some risks are associated with this approach, our research has identified a few mature existing solutions that could be further developed to support the future ORE platform.