

Thanks a lot for looking into this!
While the iPSC technology has not yet advanced to a stage where therapeutic transplants have been deemed safe, iPSCs are readily being used in personalized drug discovery efforts and understanding the patient-specific basis of disease.
I am not super familiar with the topic, but I have been told of some successful animal studies on implanting the organoid tissue into the animals from which the stem cells were derived.
This other article from 2013 lists a few concerns, and I think this is the closest to what you were looking for: https://pmc.ncbi.nlm.nih.gov/articles/PMC3931018/#sec3
Yeah, that covers nicely what I was wondering about. Especially the reason 1 (embryonic proteins not present during immune system education) and reason 2 (epigenetic changes). I can appreciate that these mechanisms might possibly cause issues, but I would be curious to learn the actual magnitude of their impact.
Yamanaka named iPSCs with a lower case “i” due to the popularity of the iPod and other products.
Oooh, that’s why! I do think iPSC looks nicer than IPSC. Not a big apple fan, though
I think the difference in time is too big. Also, in the talk page’s archive it is stated that the wikipedia was updated because of this meme, and not the other way around. This is from the talk page: