Not sure whether it’s a problem or a feature, but one concern I have with using bacteria or other organelles to break down plastics is that the resistance to what I’ll just call “rot” for the sake of simplicity, is a big part of why plastics have become so ubiquitous. In some cases plastics are definitely primarily used because of greed and cost-cutting, but there are also areas where plastic has allowed us to keep certain foods fresh for longer, and there are places in medicine where plastic is the best material for the job. I’m not saying we shouldn’t put effort into figuring out a way to clean up the mess we’ve made, but I also don’t think it’s wise to be lazy about cleaning up the mess by engineering and broadly releasing organisms that can rapidly break down plastics, because the long life of plastic is actually a feature we kinda rely on - at least until we want to dispose of the plastic.

Not that I’m not excited about the potential of breaking down plastics more rapidly, but I think there’s monkey’s paw potential there to consider.